The Lip Exo-S technique: Synergistic bioregenerative lip boosting with PDRN, Exosomes, HA Skin Boosters, and a Hyaluronic Acid Rejuvenating complex
Keywords:
PDRN, polynucelotide, skin boosters, exosomes, regenerative medicine, functional aesthetics, lip rejuvenation, lip boostingAbstract
Objective: The purpose of this study is to assess the effects of injecting the lips with a mixture of polydeoxyribonucleotide (PDRN), non-cross linked hyaluronic acid (HA) skin booster, exosomes and a hyaluronic acid rejuvenation complex vial to increase lip hydration, elasticity and rejuvenation in Middle Eastern patients.
Methods: Thirty female Middle Eastern patients who seeked a lip rejuvenation treatment at our clinic were included in the study. Using a micro cannula, a single syringe containing a combination of PDRN, non-cross linked HA skin booster, exosomes and a hyaluronic acid rejuvenation complex vial was injected in the lips of each patient. Statistical analysis was performed to evaluate the patient satisfaction score prior to and post the injection procedure through different intervals.
Results: All patients reported a marked improvement in satisfaction immediately after the injection despite the moderate swelling; we also noted an improvement in lip texture, elasticity along with a decrease in the depth of the fissures in addition to a hypopigmentation effect on the lips.
Conclusion: For lip boosting, a combination of PDRN, non-cross linked HA skin booster, exosomes and a hyaluronic acid rejuvenating complex vial can improve the quality of the lip tissue without adding volume, giving the lips a smoother texture. For lip hydration purposes, this hybrid approach yields better outcomes than the use of each product alone, which was described in our previous studies.
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Copyright (c) 2025 Noury Adel (Author)

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