Tranexamic Acid in Liposuction: A Narrative Review of Efficacy, Surgical Outcomes and Safety
Keywords:
Tranexamic Acid, liposuctionAbstract
Bruising, Bleeding, and delayed recovery are considered the main concerns after liposuction and Tranexamic acid (TXA). It is an antifibrinolytic agent that has a long record in orthopaedic surgery and cardiac arrest and has emerged as the main possible adjunct to minimise these complications. In this narrative review, a detailed summary of the current evidence on TXA use in liposuction is provided, and it is obtained from a focused literature search of Google Scholar, PubMed, and ScienceDirect for different studies published from 2018 to 2025, including randomised controlled trials, existing systematic reviews, and cohort studies. From the identified studies, both topical TXA used in tumescent solution (commonly ) and intravenous TXA (commonly between 10 and 15 mg/kg) are linked with decreased intraoperative blood loss, drain output, and ecchymosis compared with epinephrine-only or no-TXA protocols without proper thromboembolic events. Also, these evidences are obtained from small, heterogeneous studies with only outcome measures and varied dosing. Therefore, if there is any numerical estimate present that must be read with caution. However, it requires standardised and larger trials before presenting a single route, optimal dose, and a combination of protocol that can be recommended.
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