Subcision Combined with Platelet-Rich Plasma Versus Subcision Combined with Autologous Biofiller for Atrophic Acne Scars
Keywords:
Acne scars, Biofillers, SubscionAbstract
AbstractBackground: Atrophic acne scars significantly impair psychosocial well-being and quality of life (1). Subcision is a well-established technique for releasing fibrotic dermal tethering (4). Platelet-rich plasma (PRP) enhances collagen synthesis through growth factor-mediated pathways (5). Autologous plasma biofiller provides additional structural volumization while maintaining autologous safety (14). This randomized prospective clinical study done at QMC Multan compares subcision combined with PRP versus subcision combined with autologous biofiller.
Methods: Fifty-six patients (56) were randomized into two equal groups (n=28 each). Outcomes were assessed using Goodman & Baron qualitative grading system (1) and patient satisfaction scores. Results: Mean improvement was 57.8±12.4% in PRP group and 71.9±10.6% in biofiller group (p=0.0008).
Conclusion: Subcision combined with autologous biofiller provides superior and sustained clinical improvement.
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